Skip to content
Menu
eMarket

MyMD Pharmaceuticals Enrolls First Patient in Stage 2 Scientific Trial of MYMD-1 as a Treatment for Delaying Aging as well as Expanding Healthy And Balanced Lifespan

Posted on April 11, 2022

MyMD Pharmaceuticals, Inc. MyMD Pharmaceuticals Inc – Stock Price, Quote and News (” MyMD” or “the Company”), a scientific phase pharmaceutical business committed to expanding healthy lifespan, today introduced that the very first person has been enrolled in the Firm’s Stage 2 clinical test of lead candidate MYMD-1, an oral immune regulator medicine, as a treatment for delaying aging and also expanding healthy and balanced life-span.

The main endpoint for the Phase 2 double-blind, placebo-controlled scientific test is to achieve a decrease in the distributing levels of (TNF-α), tumor necrosis element receptor I (TNFRI) and IL-6. TNF-α and IL-6 are the healthy proteins in the body that cause inflammation and help turn on the process of aging. The additional steps of the test will certainly be the safety and security, tolerability, and also pharmacokinetics in this populace of patients.

” In a Phase 1 clinical trial of MYMD-1, we demonstrated the medicine’s statistically substantial effectiveness in minimizing degrees of TNF-α, a key player in causing pathological aging, in the blood. The FDA has actually accepted TNF-α decrease as the key endpoint for our Stage 2 study, which we believe settings us well for a successful Phase 2 end result,” stated Chris Chapman, M.D., President, Director as well as Chief Medical Police Officer of MyMD. “The initiation of client enrollment in this research study advancements our goal to slow the aging procedure, protect against loss of muscle cells in aging, restriction frailty, and expand healthy lifespan.”

MyMD has actually mentioned that there are no FDA-approved medicines for treating aging disorders and also extending healthy lifespan people, a market expected to be a minimum of $600 billion by 20251 according to a major investment bank. TNF-α blockers are the most recommended medications by earnings, an international market of approximately $40 billion per year,2 as well as, according to Nature Aging journal,3 a stagnation in aging that would increase life span by one year deserves $38 trillion as well as by 10 years is worth $367 trillion.

Along with aging, MYMD-1’s distinct activity in regulating the immune system and treating chronic swelling is being developed for the therapy of autoimmune illness, consisting of rheumatoid joint inflammation (RA), numerous sclerosis (MS), diabetic issues, and inflammatory digestive tract illness.

” We plan to begin creating protocols for a Stage 2 pilot study of MYMD-1 for rheumatoid arthritis early this year,” Dr. Chapman kept in mind. “The rising frequency of rheumatoid arthritis and also various other autoimmune and also inflammatory conditions are driving need for TNF inhibitors like MYMD-1, and also our team believe our orally carried out medicine with very reduced poisoning would be turbulent to the $60 billion market for RA if authorized by the FDA for this sign.”

Rheumatoid arthritis influences approximately 40 million people globally.4.

About MYMD-1.

Originally developed for autoimmune illness, MYMD-1’s key purpose is to slow down the aging process, avoid sarcopenia as well as frailty, as well as expand healthy and balanced life expectancy. Due to the fact that it can go across the blood-brain obstacle and access to the main nerves (CNS), MYMD-1 is also positioned to be a feasible therapy for brain-related problems. Its system of activity and efficacy in illness including several sclerosis (MS) as well as thyroiditis have been researched via collaborations with several scholastic establishments. MYMD-1 is likewise showing promise in pre-clinical research studies as a prospective treatment for post- COVID-19 difficulties and also as an anti-fibrotic and anti-proliferation therapeutic.

MYMD-1 has shown efficiency in pre-clinical studies in managing the immune system by performing as a selective inhibitor of lump necrosis factor-alpha (TNF-α), a chauffeur of chronic swelling. Unlike other therapies, MYMD-1 has been shown in these pre-clinical research studies to selectively block TNF-α when it becomes overactivated in autoimmune conditions and cytokine tornados, but not obstruct it from doing its normal job of being a first -responder to any regular sort of moderate infection. MYMD-1’s ease of oral dosing is one more differentiator contrasted to presently offered TNF-α blockers, all of which call for shipment by shot or infusion. No authorized TNF inhibitor has actually ever before been dosed by mouth. Furthermore, the medicine is not immunosuppressive and also has not been revealed to trigger the serious side effects usual with conventional treatments that deal with inflammation.

Regarding MyMD Pharmaceuticals, Inc

. MyMD Pharmaceuticals, Inc. (Nasdaq: MYMD), a medical stage pharmaceutical firm dedicated to prolonging healthy life-span, is focused on creating 2 novel restorative platforms that treat the root causes of disease as opposed to only attending to the signs and symptoms. MYMD-1 is a medicine system based upon a scientific phase little particle that manages the body immune system to regulate TNF-α, which drives chronic swelling, as well as other pro-inflammatory cell signaling cytokines. MYMD-1 is being created to postpone aging, rise longevity, as well as treat autoimmune illness and also COVID-19- connected depression. The Company’s 2nd medicine system, Supera-CBD, is being created to deal with persistent discomfort, dependency and epilepsy. Supera-CBD is a novel synthetic by-product of cannabidiol (CBD) and is being established to deal with and also surpass the quickly expanding CBD market, that includes both FDA approved medicines and CBD items not presently regulated as drugs. To learn more, browse through www.mymd.com.

Recent Posts

  • 5 things to understand before the stock market opens up
  • AT&T Yahoo Email Setups
  • Finland, Sweden readied to relate to sign up with NATO, a significant move for the generally neutral countries
  • Shares of Workhorse Group Inc. WKHS, -10.25% plunged 0.62 %to $3.22 Friday
  • Stocks of General Electric Co. (NYSE: GE), -6.5% dropped to $73 Monday

Tags

General Electric
©2022 eMarket | WordPress Theme by Superbthemes.com